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. 1971 Jan;68(1):48–51. doi: 10.1073/pnas.68.1.48

Chemical Modifications of Transfer RNA Species. Desulfurization with Raney Nickel

Sidney M Hecht 1,2,*, Leslie H Kirkegaard 1,2,†, Robert M Bock 1,2
PMCID: PMC391099  PMID: 4924970

Abstract

A single, modified nucleoside in Escherichia coli tRNA, 6-(3-methyl-2-butenylamino)-2-methyl-thio-9-β-D-ribofuranosylpurine, has been desulfurized with Raney nickel to afford its probable biosynthetic precursor. The limitations of the reaction at the nucleoside and tRNA levels and its lack of inhibition of the amino acid acceptor activity of tRNA are described.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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