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. 1971 Jan;68(1):234–239. doi: 10.1073/pnas.68.1.234

Genes for Neuronal Properties Expressed in Neuroblastoma × L Cell Hybrids

John Minna 1,2, Phillip Nelson 1,2, John Peacock 1,2, Devera Glazer 1,2, Marshall Nirenberg 1,2
PMCID: PMC391202  PMID: 5276295

Abstract

Neuroblastoma cells with electrically excitable membranes were fused with electrically passive L cells having a hitherto undescribed electrical marker. Hybrid cells, examined 10-40 generations after fusion, were found to be electrically excitable. The results show that at least a part of the genetic information for neuron differentiation can be functionally expressed in N × L hybrid cells. Evidence for the regulation of action potential components was also found.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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