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Synthesis of target derivatives 7–15. (a) BrCN, Dioxane, rt; (b) CS2, KOH, EtOH, reflux; (c) 1,1′-CDI, triethylamine, DMF, reflux; (d) (1) KSCN, HCl, H2O, rt; (2) NaOH 3%, 60-70°C; (e) (1) Isothiocyanate derivatives, EtOH, rt; (2) NaOH, reflux.
