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. 2013 Dec 5;137(2):420–432. doi: 10.1093/brain/awt327

Figure 4.

Figure 4

Sciatic nerve axons of merlin knockout mice show reduced axonal NRG1 expression. (A) Representative pictures of immunohistochemical stainings for neurofilaments (NF) and NRG1 on sciatic nerves of merlin isoform1-deficient mice (nf2 iso1 KO) and wild-type controls. Visualization of bound antibodies with diaminobenzidine (brown), counterstained with Mayer’s haemalum. Scale bar = 20 µm. Arrows indicate examples of unstained axons. (B and C) Percentage of NRG1-positive myelinated fibres in sciatic nerve samples of 3-week-old (B) and 8-week-old (C) nf2 iso1 knockout (KO) mice and corresponding wild-type littermates (data represent mean ± SEM; *P < 0.05).