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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1984 Aug;81(16):5247–5249. doi: 10.1073/pnas.81.16.5247

Cross-reactions of polysaccharides of fungi, molds, and yeasts in anti-pneumococcal and other antisera.

M Heidelberger, A W Bernheimer
PMCID: PMC391675  PMID: 6591189

Abstract

Cross-reactions of a number of glycans and polysaccharides isolated from fungi, molds, and yeasts in anti-pneumococcal and other antisera are tabulated and discussed insofar as possible with relation to the chemical structures of the cross-precipitating substances and the polysaccharidic antigens giving rise to the reactive antibodies. For example, the slime of Physarum polycephalum precipitated antisera to pneumococcal type 4 and Klebsiella type K1. The polysaccharides of type 4 and K1 contain pyruvic acid in acetal linkage on hydroxyls 2 and 3 of sugars. Therefore, pyruvic acid was looked for and found in Physarum slime. Numerous other relations between chemical structure and immunological specificity are given.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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