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. 1984 Dec;81(24):7937–7940. doi: 10.1073/pnas.81.24.7937

Interferon induces pulmonary cysts in A2G mice.

D Woodrow, J Moss, I Gresser
PMCID: PMC392268  PMID: 6595668

Abstract

Suckling A2G mice were treated for the first week of life with either partially purified or electrophoretically pure mouse alpha/beta interferon. All mice subsequently developed multiple large pulmonary cysts. The lesions were never found in interferon-treated Swiss mice and only very infrequently in interferon-treated BALB/c or F1 Swiss/A2G mice. These observations show that a brief exposure of suckling A2G mice to alpha/beta interferon can result in a severe disease that is determined by the mouse genotype.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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