Table 3.

Adjusted^* Odds Ratio (and 95% confidence interval) from logistic^† and GEE^‡ regression models for quartiles of AGE-LDL-IC in relation to elevated internal carotid IMT and IMT progression.

	6 Year ICA IMT†	12 Year ICA IMT†	IMT Progression Year 1 to 12†	Elevated ICA IMT‡
Model 1*
Lowest Quartile	1.00	1.00	1.00	1.00
Quartile 2	1.43 (0.60-3.41)	1.38 (0.60-3.21)	1.49 (0.62-3.59)	1.54 (0.73-3.24)
Quartile 3	1.95 (0.85-4.46)	1.81 (0.77-4.24)	2.20 (0.92-5.24)	2.48 (1.22-5.06)
Quartile 4	2.95 (1.33-6.55)	2.82 (1.25-6.39)	4.03 (1.72-9.45)	4.14 (2.06-8.31)
ROC AUC	0.754	0.805	0.792
Model 2*
Lowest Quartile	1.00	1.00	1.00	1.00
Quartile 2	1.11 (0.45-2.71)	1.11 (0.46-2.69)	1.27 (0.50-3.20)	1.34 (0.62-2.93)
Quartile 3	1.65 (0.72-3.78)	1.65 (0.71-3.82)	2.15 (0.88-5.21)	2.04 (0.98-4.24)
Quartile 4	2.05 (0.88-4.74)	1.96 (0.80-4.79)	3.50 (1.38-8.86)	2.95 (1.37-6.34)
ROC AUC	0.784	0.839	0.826
Model 3*
Lowest Quartile	1.00	1.00	1.00	1.00
Quartile 2	1.26 (0.49-3.26)	0.87 (0.32-2.40)	0.98 (0.35-2.81)	1.21 (0.51-2.87)
Quartile 3	1.80 (0.72-4.47)	1.64 (0.63-4.27)	1.87 (0.72-4.89)	1.82 (0.82-4.03)
Quartile 4	2.63 (1.05-6.55)	2.19 (0.80-5.96)	3.61 (1.34-9.68)	3.07 (1.34-7.06)
ROC AUC	0.784	0.854	0.841

^*Models are as specified in Table 2.