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. 1978 Jul;75(7):3455–3458. doi: 10.1073/pnas.75.7.3455

Activated human T lymphocytes display new surface glycoproteins.

L C Andersson, C G Gahmberg, A K Kimura, H Wigzell
PMCID: PMC392796  PMID: 308233

Abstract

We have analyzed the surface glycoproteins of resting and in vitro activated human T lymphocytes by the galactose oxidase/NaB3H4 and the periodate/NaB3H4 labeling techniques. The labeled glycoproteins were separated by polyacrylamide slab gel electrophoresis and visualized by fluorography. A "new" glycoprotein with an apparent molecular weight of 130,000 (GP130) was strongly labeled on alloantigen-activated T blasts but only weakly or not at all on mitogen-stimulated T blasts and resting T lymphocytes. These results demonstrate that human T cells, as earlier found in the mouse system, express different surface molecules in relation to the particular mode of activation and stage of differentiation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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