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. 1978 Aug;75(8):3737–3741. doi: 10.1073/pnas.75.8.3737

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

J G Sutcliffe
PMCID: PMC392861  PMID: 358200

Abstract

I have determined the nucleotide sequence of the ampicillin resistance gene of pBR322, an Escherichia coli plasmid that encodes a penicillin beta-lactamase. This gene codes for a protein of 286 amino acid residues. The first 23 amino acids presumably form a signal for secretion, because they do not appear in the mature enzyme, whose partial amino acid sequence has been determined independently.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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