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. 1978 Aug;75(8):3863–3866. doi: 10.1073/pnas.75.8.3863

Association of mitochondria with microtubules in cultured cells.

M H Heggeness, M Simon, S J Singer
PMCID: PMC392888  PMID: 80800

Abstract

By indirect immunofluorescence techniques, microtubules and mitochondria were localized in normal rat kidney cells, human WI38 fibroblasts, mouse peritoneal macrophages, and a putative smooth muscle rat cell line, in monolayer culture. The mitochondria were found to be arranged along the cytoplasmic microtubules in each cell type. Disruption of the microtubules with colcemid caused a redistribution of the mitochondria in these cells. There was no correlation between the location of the mitochondria and actin-containing filaments. This evidence suggests that mitochondria are directly or indirectly associated with microtubules in these cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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