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. 1978 Nov;75(11):5260–5263. doi: 10.1073/pnas.75.11.5260

Interacting enzyme systems at steady state: further Monte Carlo calculations on two-state molecules.

T L Hill, Y D Chen
PMCID: PMC392940  PMID: 281678

Abstract

In this work, Monte Carlo calculations were made on a 10 x 10 lattice of two-state, steady-state enzyme molecules in two special cases for which the Bragg-Williams (mean field) approximation had earlier produced some very interesting phase-transition properties. The Monte Carlo results proved to be similar to Bragg-Williams in some respects but not in others. The discrepancies are attributed primarily to; (i) inadequate treatment by Bragg-Williams of strong negative cooperativity; and (ii) the finite size of the 10 x 10 lattice used in the exact calculations.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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