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. 1978 Nov;75(11):5565–5569. doi: 10.1073/pnas.75.11.5565

Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).

D Solter, B B Knowles
PMCID: PMC393007  PMID: 281705

Abstract

A monoclonal antibody derived by fusion of mouse myeloma cells with spleen cells from a mouse immunized with F9 teratocarcinoma cells is described. This antibody, which reacts with embryonal carcinoma cells of mouse and human origin and with some preimplantation stage mouse embryos, defines an embryonic stage-specific antigen. This stage-specific antigen (SSEA-1) is first detected on blastomeres of 8-cell stage embryos. Trophectodermal cells are transitorily positive; however, each cell in the inner cell mass eventually expresses this antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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