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. 1978 Nov;75(11):5665–5668. doi: 10.1073/pnas.75.11.5665

Immunization against malaria with antigen from Plasmodium falciparum cultivated in vitro.

R T Reese, W Trager, J B Jensen, D A Miller, R Tantravahi
PMCID: PMC393028  PMID: 103100

Abstract

Aotus monkeys, which are generally killed when infected with the human malaria parasite Plasmodium falciparum, have been identified and grouped by karyotype. These animals were immunized with parasite material obtained from P. falciparum cultivated in vitro which had been maintained in culture for over a year. When sufficient amounts of this antigenic material were used with a synthetic muramyl dipeptide (MDP), protective immunity was induced without presenting the antigen in complete Freund's adjuvant.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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