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. 1978 Dec;75(12):5807–5811. doi: 10.1073/pnas.75.12.5807

Cell-free synthesis and processing of the proteins of poliovirus.

D S Shih, C T Shih, O Kew, M Pallansch, R Rueckert, P Kaesberg
PMCID: PMC393064  PMID: 215997

Abstract

Poliovirus RNA can be translated completely and accurately in rabbit reticulocyte lysates; the nascent poly-protein is processed to give primary products 1a, X, and 1b indistinguishable from those made in poliovirus-infected HeLa cells. The capsid precursor protein 1a is processed to form the capsid proteins VP0, VP1, and VP3, while the noncapsid precursor 1b is processed to form protein 2.

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Selected References

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