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. 1977 Jan;74(1):139–143. doi: 10.1073/pnas.74.1.139

Distinctions between the two-state and sequential models for cooperative ligand binding.

R E Gibson, S A Levin
PMCID: PMC393213  PMID: 264668

Abstract

The two-state and sequential models for positive cooperativity in ligand binding can produce significantly different theoretical binding curves when presented in a Scatchard plot. The conditions that produce the greatest differences have been examined. The theoretical differences have been used to select the two-state model as the best model for describing the binding of acetylcholine to acetylcholine receptors that have been solubilized by Triton X-100 and sodium cholate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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