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. 1977 Jan;74(1):319–323. doi: 10.1073/pnas.74.1.319

Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells.

R E Fournier, F H Ruddle
PMCID: PMC393251  PMID: 264685

Abstract

In this report, we describe the production and characterization of proliferating hybrid cell populations generated by fusion of murine microcells with intact mouse, Chinese hamster, and human recipient cells. The microcell hybrids so produced contained one to five intact murine chromosomes derived from the microcell donor. these transferred chromosomes were maintained as functioning genetic elements in the hybrid cells. Our results firmly establish subnuclear particle-mediated chromosome transfer as a valid somatic cell genetic tool.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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