Fig. 3.

(A) The merged fluorescence and white light images (top panel) show the accumulation of fibrin-affinity probes at the TiO₂ injection sites, but not the control site (saline injection). The mean fluorescence intensities at the TiO₂ injection sites, but not saline injection sites, increased with time (bottom panel). (B) In vivo fluorescence imaging post-injection illustrates the diminishing accumulation of fibrin-affinity probes around TiO₂ with heparin treatment in comparison with TiO₂ alone within 1 h. (C) Quantification of fluorescence intensities within 1 h. Each mouse in test groups (n = 4) was treated with the probe (60 μL, 0.5 mg/mL). Error bars represent standard deviation (s.d.), * denotes p < 0.05. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)