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. 1983 Feb;80(4):931–934. doi: 10.1073/pnas.80.4.931

Crystallization of a common cold virus, human rhinovirus 14: “Isomorphism” with poliovirus crystals

John W Erickson *, Elizabeth A Frankenberger *, Michael G Rossmann *,†, G Shay Fout ‡, K C Medappa ‡, Roland R Rueckert ‡
PMCID: PMC393501  PMID: 6302674

Abstract

Crystals of rhinovirus 14 have been grown reproducibly. They diffract x-rays to a resolution of at least 3.5 Å. The orthorhombic crystal unit cell contains two virions, each situated on a crystallographic twofold axis. At less than 30-Å resolution, the space group approximates to 1222 with the particles possessing 222 pseudo crystallographic symmetry. The crystals are “isomorphous” with type I polio crystals [Finch, J. T. & Klug, A. (1959) Nature (London) 183, 1709-1714; Hogle, J. M. (1982) J. Mol. Biol. 160, 663-668], suggesting some similarities of structure between enteroviruses and rhinoviruses.

Keywords: picornavirus structure, x-ray diffraction, reproducibly grown crystals, high-resolution data

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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