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. 1983 Feb;80(4):1092–1095. doi: 10.1073/pnas.80.4.1092

Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F. M. Burnet revisited

Richard A Finkelstein *, Mary Boesman-Finkelstein †, Peter Holt *
PMCID: PMC393534  PMID: 6341990

Abstract

Cholera vibrios produce a single polymeric protein that (i) causes hemagglutination; (ii) appears to participate in their attachment to gut epithelium; (iii) may mediate their detachment from gut epithelium; and (iv) is a protease that hydrolyzes fibronectin and mucin, cleaves lactoferrin, and nicks the A subunit of the choleragen-related heat-labile enterotoxin of Escherichia coli.

Keywords: lactoferrin, mucinase, enterotoxin, adherence, immunity

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Selected References

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