Table 1.
Males | N | colon | Proximal SI | Distal SI |
---|---|---|---|---|
Kcnq1 +/+ | 30 | 1.8 ± 1.7 | 11 ± 8 | 56 ± 41 |
Kcnq1 +/− | 34 | *3.8 ± 2.3 | *18 ± 13 | *76 ± 38 |
Kcnq1 −/− | 10 | 2.6 ± 2.8 | *36 ± 16 | 52 ± 43 |
Females | ||||
Kcnq1 +/+ | 26 | 1.2 ± 1.7 | 14 ± 9 | *58 ± 25 |
Kcnq1 +/− | 46 | *2.5 ± 2.2 | 20 ± 12 | *84 ± 37 |
Kcnq1 −/− | 13 | 2.1 ± 2.0 | *22 ± 11 | 30 ± 16 |
ApcMin Kcnq1+/+, ApcMin Kcnq1+/− and ApcMinKcnq1−/− mice were sacrificed at 120 days of age and tumors counted and measured.
P values: < 0.05; Two-sided P values for tumor counts were determined by use of the Wilcoxon Rank Sum Test comparing gender and age-matched classes produced in the same genetic crosses.