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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1983 May;80(9):2589–2590. doi: 10.1073/pnas.80.9.2589

Derivation of the relation between the linear Onsager coefficients and the equilibrium one-way cycle fluxes of a biochemical kinetic diagram

Terrell L Hill 1
PMCID: PMC393871  PMID: 16593306

Abstract

The Onsager flux-force coefficients Lij for any biochemical system at a steady state near equilibrium have a simple interpretation: they are linear combinations of the equilibrium one-way cycle fluxes of the kinetic diagram for the system. An explicit and general expression for Lij is derived. This supplements the more pedagogical argument published elsewhere, which was based on a particular special case.

Keywords: enzyme kinetics, flux-force relation, near-equilibrium steady state, irreversible thermodynamics

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