Correction for Chu et al., Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH₂

BIOCHEMISTRY Correction for “Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH₂,” by Pei-Hsuan Chu, Teng-Yi Huang, Jason Williams, and D. W. Stafford, which appeared in issue 51, December 19, 2006, of Proc Natl Acad Sci USA (103:19308–19313; first published December 12, 2006; 10.1073/pnas.0609401103).

The authors note that Fig. 5 and its corresponding legend appeared incorrectly. The corrected figure and its corrected legend appear below.

Fig. 5.

Conversion of vitamin K to vitamin KH₂ by VKOR. The reaction was performed by using purified VKOR that had been dialyzed in the presence of THP. VKOR activity is represented as turnover number per second. Bar 1, DTT with elution buffer as background control; Bar2, purified VKOR after dialysis against buffer A with 4 mM THP. Data are represented as mean ± SD (n = 3).

Also, the authors note that on page 19312, right column, 3rd full paragraph, line 5 “The reaction was carried out for 1 hr.” should instead appear as “The reaction was carried out for 20 min.”