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Gene-gene interaction analysis in DKK3 rs3206824-sFRP4 rs1802074
| DKK3 A (GG/GA+AA)-sFRP4 B (AA/AG+GG) | renal cancer (n=210) | control (n=200) | OR (95% CI) | p-value |
|---|---|---|---|---|
| n (%) | n (%) | |||
| GG-AA | 27 (13) | 9 (4.5) | 1 (reference) | |
| GG-AG/GG | 123 (58) | 95 (47.5) | 0.43 (0.19–0.96) | 0.04 |
| GA/AA-AA | 9 (5) | 9 (5) | 0.33 (0.10–0.20) | 0.06 |
| GA/AA-AG/GG | 51 (24) | 87 (43.5) | 0.19 (0.09–0.45) | <0.0001 |
