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. 2014 Feb 3;3(2):e86. doi: 10.1038/oncsis.2013.48

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Copyright © 2014 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Positive correlation between NDRG2 and p-Smad2/3 in colorectal cancer tissues. (a) IHC staining of NDRG2 and p-Smad2/3 in human adjacent normal and cancerous colon samples from patients at different stages. Case 1 is from a stage III patient, and Case 2 is from a stage II patient. Original magnification: × 5, × 40 or × 100. (b, c) Relative expression level of p-Smad2/3 and NDRG2 in human tissue samples. Student's t-test was applied for statistical analyses. *P<0.05, which was considered significantly different. (d) Correlation between NDRG2 and p-Smad2/3 expression with linear regression and Pearson's correlation significance (P<0.001, ANOVA test).