Table 1.
—Clinical Characteristics of Subjects With CF
| Characteristic | Mean (SD) | No. (%) |
| Female | … | 15 (42.9) |
| Age, y | 11.1 (2.6) | … |
| CF genotype | ||
| F508del/F508del | … | 14 (40) |
| F508del/other | … | 15 (43) |
| Other/other | … | 6 (17) |
| FVC % predicted | 95.5 (17.6) | … |
| FEV1 % predicted | 95.3 (15.0) | … |
| FEF25-75 % predicted | 84.7 (25.2) | … |
| RV % predicteda | 128.5 (49.8) | … |
| RV/TLCa | 27.1 (9.4) | … |
| Weight, percentile | 37.7 (24.9) | … |
| Height, percentile | 34.9 (25.7) | … |
| BMI | 17.3 (2.3) | … |
| BMI, percentile | 42.3 (25.0) | … |
| Pseudomonas aeruginosab | … | 6 (17) |
| Staphylococcus aureusb | … | 16 (46) |
CF = cystic fibrosis; FEF25-75 = midvolume forced expiratory flow; RV = residual volume; TLC = total lung capacity.
a
RV and RV/TLC were available from 28 of 35 subjects.
b
Respiratory culture data were available from 32 of 35 subjects (91%) who expectorated induced sputum samples for microbial analysis at their baseline visit.