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Journal of Oral Biology and Craniofacial Research logoLink to Journal of Oral Biology and Craniofacial Research
. 2012 Feb 8;1(1):41–43. doi: 10.1016/S2212-4268(11)60010-9

Periodontal regeneration in deep intrabony periodontal defect using hydroxyapatite particles with platelet rich fibrin membrane–a case report

Pavitra Rastogi a,*, Himani Saini b, Rameshwari Singhal c, Jaya Dixit d
PMCID: PMC3942002  PMID: 25756017

Abstract

Background

Growth factors such as platelet-derived growth factors exert potent effect on wound healing including the regeneration of periodontium. Platelet-rich fibrin (PRF) membrane provides a concentrate of such growth factors, accelerating the wound healing process.

Materials and Methods

In this case report, regeneration of the deep periodontal intrabony defect was attempted using hydroxyapatite particles mixed in the PRF membrane to assess if regeneration of new bone is possible.

Results and Conclusion

This resulted in a rapid and complete healing with the decrease in the pocket depth and a gain in the clinical attachment level. Rapid regeneration of the periodontium can be achieved with bone substitutes by incorporating the various growth factors from autogenous blood.

Key Words: Bone substitutes, growth factors, hydroxyapatite, periodontal regeneration, platelet-rich fibrin membrane

Full Text

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