Table 1.
Experiment 1. Various acute psychological and social stressors | ||||
Groups | n | Open arm | Closed arm | % Open arm |
HAN | 6 | 5.33 ± 1.86 | 9.83 ± 2.24 | 36.59 ± 9.25 |
SC | 6 | 5.33 ± 1.33 | 10.83 ± 1.85 | 30.93 ± 13.73 |
Novel | 6 | 7.33 ± 1.67 | 7.83 ± 2.23 | 51.35 ± 28.09 |
IMO | 6 | 1.03 ± 0.37 | 6.67 ± 1.65 | 15.83 ± 6.38 |
Brief SD | 8 | 4.25 ± 1.91 | 8.75 ± 2.11 | 33.08 ± 8.89 |
Prolonged SD | 7 | 3.43 ± 0.75 | 10.43 ± 1.17 | 23.99 ± 3.55 |
Experiment 2. Predictable vs. unpredictable immobilization | ||||
Groups | n | Open arm | Closed arm | % Open arm |
HAN | 11 | 5.55 ± 1.12 | 9.54 ± 1.04 | 34.96 ± 5.69 |
Acute IMO | 6 | 1.50 ± 0.72 | 9.83 ± 2.83 | 10.99 ± 6.05 |
3 day pIMO | 8 | 4.13 ± 1.01 | 8.13 ± 1.76 | 35.35 ± 8.03 |
7 day pIMO | 6 | 3.50 ± 1.52 | 14.00 ± 1.86 | 17.64 ± 3.97 |
3 day uIMO | 7 | 2.00 ± 1.05 | 7.29 ± 1.74 | 14.15 ± 5.50 |
7 day uIMO | 6 | 2.05 ± 0.86 | 9.67 ± 3.40 | 15.16 ± 6.02 |
Note. Values represent frequency of entries into the open and closed arms on the elevated plus maze as well as the percentage of open arm entries (open arm entries vs. total arm entries). Behaviors are reported as means and standard errors. Groups include handled controls (HAN), social controls (SC), and females exposed to novel environment stress (Novel), immobilization (IMO or acute IMO), brief social defeat (Brief SD), prolonged social defeat (Prolonged SD), 3 day predictable IMO (3 day pIMO), 7 day predictable IMO (7 day pIMO), 3 day unpredictable IMO (3 day uIMO), and 7 day unpredictable IMO (7 day uIMO).3 day uIMO