Figure 3.

Detection of ISA QTL for 11 phenotypes. LOD scores are plotted for all phenotypes tested in this study using the IGV browser (Robinson et al. 2011) (Mendelian traits, blue; fitness traits in rich media, black; high temperature, red; high-salt, green; nonfermentable carbon sources, purple; 5-FU, gray). QTL containing putative causative variants are marked with a gray dashed line and labeled with the gene. Gene variants that were confirmed by allele exchange or by individual growth of RHS strains (for CRG1) in this study are marked with a star at the respective phenotype. Two gene variants were found to modify more than one phenotype: MKT1 (high temperature, ethanol, 5-FU) and TAO3 (high temperature, glycerol).