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Canadian Journal of Surgery logoLink to Canadian Journal of Surgery
. 1997 Oct;40(5):368–374.

Prevalence of heterotopic ossification in cemented versus noncemented total hip joint replacement in patients with osteoarthrosis: a randomized clinical trial

K Naresh K Nayak *, Brian Mulliken, Cecil H Rorabeck *,, Robert B Bourne *, Michael R Woolfrey
PMCID: PMC3950113  PMID: 9336527

Abstract

Objective

To determine the prevalence of heterotopic bone formation in cemented versus noncemented total hip joint replacement.

Design

A prospective randomized controlled trial. Follow-up ranged from 2 to 6 years (mean 4 years).

Setting

A university hospital.

Patients

Two hundred and twenty-six patients who had primary or secondary osteoarthrosis of the hip were stratified according to type of fixation, surgeon and age. Patients were randomized within strata: 112 received noncemented total hip prostheses and 114 received cemented prostheses. The 2 groups were similar with respect to age and sex.

Intervention

Primary total hip arthroplasty. A cemented (methylmethacrylate) or noncemented prosthesis was inserted by a lateral surgical approach.

Main outcome measure

The Brooker classification was used to grade heterotopic bone formation from postoperative radiographs.

Results

Overall, 148 (66%) hips had no heterotopic ossification, 56 (25%) were Brooker class I, 14 (6%) were class II, 8 (3%) were class III and none were class IV. In the noncemented group of patients, 76 (68%) hips had no heterotopic ossification, 25 (22%) were Brooker class I, 7 (6%) were class II, 4 (4%) were class III and none were class IV. In the cemented group of patients, 72 (63%) hips had no heterotopic ossification, 31 (27%) hips were Brooker class I, 7 (6%) were class II, 4 (4%) were class III and none were class IV.

Conclusion

There was no significant difference in the prevalence of heterotopic ossification between cemented and noncemented total hip replacements in patients with osteoarthrosis.

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