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. 1994 Jun 1;13(11):2725–2734. doi: 10.1002/j.1460-2075.1994.tb06563.x

Copy-choice illegitimate DNA recombination revisited.

E d'Alençon 1, M Petranovic 1, B Michel 1, P Noirot 1, A Aucouturier 1, M Uzest 1, S D Ehrlich 1
PMCID: PMC395147  PMID: 8013470

Abstract

Nearly precise excision of a transposon related to Tn10 from an Escherichia coli plasmid was used as a model to study illegitimate DNA recombination between short direct repeats. The excision was stimulated 100-1000 times by induction of plasmid single-stranded DNA synthesis and did not involve transfer of DNA from the parental to the progeny molecule. We conclude that it occurred by copy-choice DNA recombination, and propose that other events of recombination between short direct repeats might be a result of the same process.

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Selected References

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