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Reduction of endogenous RasGRP3 expression inhibited tumor formation of SK-MEL-5 cell lines.
| Cell Line (SK-MEL-5) | Total tumor/Total injection | Tumor weight (mg) | ||
|---|---|---|---|---|
|
| ||||
| Deoxytetracycline | Deoxytetracycline | |||
| − | + | − | + | |
| Control | 14/16 | 14/16 | 18.0±2.8 | 17.5±3.0 |
| sh854 | 11/16 | 9/16 | 11.7±2.3 | 5.2±1.6 |
| sh854m | 12/16 | 10/16 | 13.1±2.9 | 11.7±3.1 |
