Abstract
When autotrophically growing cultures of Chlorella are treated with levulinic acid, δ-aminolevulinic acid is excreted into the medium, providing a direct demonstration of α-aminolevulinic acid production in a green plant. Evidence is presented which indicates that α-aminolevulinic acid formation may be the the rate-controlling step of chlorophyll synthesis in Chlorella, and that control of the rate of α-aminolevulinic acid synthesis may be exerted at the level of production and breakdown of an enzyme which catalyzes its formation.
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- BURNHAM B. F., PIERCE W. S., WILLIAMS K. R., BOYER M. H., KIRBY C. K. delta-aminolaevulate dehydratase from Rhodopseudomonas spheroides. Biochem J. 1963 Jun;87:462–472. doi: 10.1042/bj0870462. [DOI] [PMC free article] [PubMed] [Google Scholar]
- GIBSON K. D., LAVER W. G., NEUBERGER A. Initial stages in the biosynthesis of porphyrins. 2. The formation of delta-aminolaevulic acid from glycine and succinyl-coenzyme A by particles from chicken erythrocytes. Biochem J. 1958 Sep;70(1):71–81. doi: 10.1042/bj0700071. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gassman M., Pluscec J., Bogorad L. delta-Aminolevulinic Acid Transaminase in Chlorella vulgaris. Plant Physiol. 1968 Sep;43(9):1411–1414. doi: 10.1104/pp.43.9.1411. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Granick S. The induction in vitro of the synthesis of delta-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals. J Biol Chem. 1966 Mar 25;241(6):1359–1375. [PubMed] [Google Scholar]
- KIKUCHI G., KUMAR A., TALMAGE P., SHEMIN D. The enzymatic synthesis of delta-aminolevulinic acid. J Biol Chem. 1958 Nov;233(5):1214–1219. [PubMed] [Google Scholar]
- MAUZERALL D., GRANICK S. The occurrence and determination of delta-amino-levulinic acid and porphobilinogen in urine. J Biol Chem. 1956 Mar;219(1):435–446. [PubMed] [Google Scholar]
- Nandi D. L., Shemin D. Delta-aminolevulinic acid dehydratase of Rhodopseudomonas spheroides. 3. Mechanism of porphobilinogen synthesis. J Biol Chem. 1968 Mar 25;243(6):1236–1242. [PubMed] [Google Scholar]
- Shugarman P. M., Appleman D. Natural Variations in the Physiological Characteristics of Growing Chlorella Cultures. Plant Physiol. 1965 Jan;40(1):81–84. doi: 10.1104/pp.40.1.81. [DOI] [PMC free article] [PubMed] [Google Scholar]