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. 1970 Sep;46(3):471–474. doi: 10.1104/pp.46.3.471

Effects of Gramicidin on Corn Mitochondria 1

Raymond J Miller a, W S Dumford a,2, D E Koeppe a
PMCID: PMC396618  PMID: 5481397

Abstract

The effects of gramicidin D, S, and J on corn mitochondria respiration and swelling were studied. Only gramicidin D was found to have any pronounced effect on mitochondrial swelling. In buffered KCl gramicidin D produced a rapid, respiration-independent swelling which was not reversed with respiratory inhibitors or substrate exhaustion. The respiration rate of exogenous reduced nicotinamide adenine dinucleotide was stimulated by all three gramicidins, but the effects on malate-pyruvate and succinate respiration depended on the type of gramicidin and the reaction media. The respiration effects of gramicidin D may be due to action at specific sites for each substrate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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