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. 2014 Mar 26;9(3):e93142. doi: 10.1371/journal.pone.0093142

Correction: Influenza A(H1N1)pdm09 and Cystic Fibrosis Lung Disease: A Systematic Meta-Analysis

The PLOS ONE Staff
PMCID: PMC3966849

In Figure 1, “Symptoms of Influenza A(H1N1)pdm09 infection in CF, asthmatics and healthy controls,” some of the bars are incorrectly shaded. Please see the corrected Figure 1 here.

Figure 1. Symptoms of Influenza A(H1N1)pdm09 infection in CF, asthmatics and healthy controls.

Figure 1

Frequency of presenting symptoms in CF patients, asthmatics and healthy controls from four studies of Influenza A(H1N1)pdm09 infection in CF patients [39]–[42], and a study of asthmatics and healthy controls [13] during the 2009 pandemic.

Table 1 has been corrected for improved readability. Please see the corrected Table 1 here.

Table 1. Characteristics, treatment and outcome of Influenza A(H1N1)pdm09-infected CF patients.

Country Inf A(H1N1)pdm09 infection in CF patients Characteristics of CF patients infected with Inf A(H1N1)pdm09 (%) Treatment (%) Outcome (%) Conclusion / Recommendation Ref
N 1 Age 2 Incidence* (%) P. aerug. // B. cepacia coinfection Pancreatic Insufficiency FEV1 pred3 Vacc Oseltamivir // Antibiotics Hospital admission ICU 4 or ventilation CFR 5
Europe# 110 13 2.3* n.r. 84 69 8.8 81 // 66 48 5.4 2.7 awareness, infection control, vaccination campaign [39]
Italy# 68 15 53** 48.5 // 8.8 89.7 53 13.2 82 // 68 69 1.5 ventilation 13.2 on oxygen 4.4 annual vaccination in adult CF patients [41]
Australia 11 22 4.4* 100 // 1 n.r. 66 n.av. 100 // 75 63 n.r. n.r. prompt commencement of oseltamivir and antibiotic therapy [42]
UK 13 22 4* 100 // n.r. n.r. 51.4 n.r. 100 // 100 69 0 n.r. generally mild illness in CF, potentially more virulent pandemic in the future [40]
1

Number of Influenza A(H1N1)pdm09 positive CF patients

2

Mean age (years)

3

Mean of all CF patients studied

4

Intensive care unit

5

Case fatality rate

#

multicenter surveys; *incidence of Inf A(H1N1)pdm09 infections in CF patients **incidence of Inf A(H1N1)pdm09 infections relating to CF patients with influenza-like illness (ILI); n.r. – not reported; Vacc – Vaccination coverage; P. aerug.  =  Pseudomonas aeruginosa; B. cepacia  =  Burkholderia cepacia.

Reference


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