Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison of representative structures from class A–D sortases. B. anthracis class D enzymes are structurally similar to class A enzymes. BaSrtC lacks the long, structured, β6–β7 loop (yellow) present in class B enzymes, but the appearance of a short 310-helix in this region likely indicates the existence of a rigid substrate-binding pocket, similar to BaSrtA. BaSrtC also lacks the structured N-terminal lid present in class C enzymes (green).
