. 2014 Apr 1;5(2):e01017-14. doi: 10.1128/mBio.01017-14

TABLE 1 .

Constitutive expression of bbd18 prevents B. burgdorferi infection in mice by needle inoculation

Strain^a	No. of seropositive mice/no. of mice injected^b	No. of tissue isolates/no. of mice injected (ear, bladder, joint)^c
WT	5/5	5/5, 5/5, 5/5
WT+cBBD18	0/10^d	0/10, 0/10, 0/10^d
WT/chase	4/5	4/5, 4/5, 4/5

^{^a}

Mice were inoculated with B. burgdorferi strains S9 (WT), S9/pBSV2*flaBp-bbd18 (WT+cBBD18), or S9/chase-pBSV2G (WT/chase).

^{^b}

Seroconversion to B. burgdorferi whole-cell lysates was assessed by immunoblotting 3 weeks after needle inoculation of 10⁴ spirochetes.

^{^c}

Isolation of spirochetes from mouse tissues was attempted 5 weeks after inoculation.

^{^d}

P value of <0.0005 compared to WT and P value of <0.005 compared to WT/chase, using Fisher’s exact test.