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. 1985 May;82(10):3207–3211. doi: 10.1073/pnas.82.10.3207

Rapid processing of the carboxyl terminus of a trypanosome variant surface glycoprotein.

J D Bangs, D Hereld, J L Krakow, G W Hart, P T Englund
PMCID: PMC397744  PMID: 3858818

Abstract

The variant surface glycoprotein of the parasite Trypanosoma brucei contains a glycolipid of unknown structure covalently attached to its COOH terminus. We have shown, by using metabolic labeling with [35S]methionine or [3H]myristic acid, precipitation with specific antibodies, and NaDodSO4/polyacrylamide gel electrophoresis, that this glycolipid is attached to the variant surface glycoprotein polypeptide within 1 min after its translation.

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