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Journal of Basic and Clinical Pharmacy logoLink to Journal of Basic and Clinical Pharmacy
. 2010 Aug 15;1(3):187–190.

CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF SOLIDAGO CANADENSIS LINN. ROOT ESSENTIAL OIL

Devendra Mishra 1,*, Shivani Joshi 2, Ganga Bisht 2, Sangeeta Pilkhwal 3
PMCID: PMC3979189  PMID: 24825986

Abstract

The essential oil from the roots of Solidago canadensis Linn. (fam. Asteraceae) was analyzed by GC, GC/MS and NMR spectroscopy. Thirty nine constituents comprising 75.4% of the total oil were identified from the oil. Thymol constituted 20.25% of the oil followed by α-copaene (6.26%) and carvacrol (5.51%). The antimicrobial activity of the oil was evaluated using disc diffusion method. Results showed that the oil exhibited significant antibacterial activity against S. feacalis and E. coli whereas it showed moderate antifungal activity against C. albicans

KEYWORDS: Solidago canadensis, essential oil, thymol, antimicrobial activity, disc diffusion

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