. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Laryngoscope. 2013 Oct 22;124(4):E107–E114. doi: 10.1002/lary.24412

Table 5.

Correlation coefficients (r_s) between gene expression, disease-specific QOL, and clinical measures of disease severity in patients with CRS.

Inflammatory mediators:	RSDI Physical	RSDI Functional	RSDI Emotional	RSDI Total	SNOT-22	Endoscopy Score	CT Score	B-SIT Olfactory Score
IL-4	0.125	−0.063	−0.332	−0.096	−0.014	−0.206	−0.089	−0.138
IL-13	−0.318	−0.252	−0.291	−0.285	−0.467^**	−0.250	−0.461^**	0.118
TGF-β	0.177	0.293	0.173	0.248	0.096	−0.136	−0.438	−0.059

r_s=Spearman’s correlation coefficient; QOL=quality-of-life; CRS=chronic rhinosinusitis; RSDI=Rhinosinusitis Disability Index; SNOT-22=Sinonasal Outcome Test-22; CT=computed tomography; B-SIT=Brief Smell Identification Test; IL=interleukin; TGF-β=transforming growth factor-beta.

^**

indicates p-value less than 0.05.