Biochemical product recovery
http://www.rpi.edu/dept/chem-eng/Biotech-Environ/DOWNSTREAM/fixed.htm
This site provides a good overview of the different aspects of product recovery in biotechnology, from proteins to small molecules.
Downstream processing
http://en.wikipedia.org/wiki/Downstream_processing
Downstream processing refers to the recovery and purification of products from biotechnological processes. This short article provides links to further information on different aspects of the process.
In situ product recovery
https://www.cell.com/trends/biotechnology/abstract/0167-7799(84)90022-2
This review article discusses innovative methods for bioprocess product recovery.
Purification of isoprene from renewable resources
https://www.google.com/patents/WO2011075534A2?cl=en
Isoprene boils at the growth temeprature of Escherichia coli cells, and this makes for a convenient recovery system in which isoprene gas can be recovered from fermentors.
Membrane extraction system for ethanol
http://www1.eere.energy.gov/manufacturing/intensiveprocesses/pdfs/adv_water_removal_mse.pdf
There is a significant cost in money and energy to extract ethanol biofuels from aqueous media as ethanol is highly soluble in water and has a fairly high boiling point. In this context, this file describes a membrane technology for removing ethanol from fermentation broths.
Ethanol stripping from fermentors
https://workspace.imperial.ac.uk/centreforprocesssystemsengineering/Public/MSc%20Thesis/2010%20MSc%20Thesis/2010.2%20-%20Andrew%20Amenaghawon%20.pdf
Because ethanol recovery is a major cost in money and energy, less expensive methods have been sought. This thesis deals with using gas stripping methods.
A survey of separation systems for ethanol
http://scholar.lib.vt.edu/theses/available/etd-03052009-175635/unrestricted/Thesis_ETD8.pdf
This thesis describes a flash evaporation process for efficient removal of ethanol from aqueous fermentation broths.
Acetone-butanol-ethanol fermentation recovery process
http://pubs.acs.org/doi/abs/10.1021/ef401706k
This paper describes a novel membrane system for solvent recovery from the Clostridium acetobutylicum-mixed solvent fermentation.
Method of recovering 1,3-propanediol from fermentation broth
http://www.google.com/patents/US6479716
1,3-Propanediol is an important commodity chemical made in large-scale fermentation processes. The product was initially recovered by solvent extraction. This patent describes the use of a cationic resin to bind the chemical and remove it from the fermentation broth.
Extraction of antibiotics
http://www.westfalia-separator.com/applications/chemical-pharmaceutical-technology/extraction/antibiotics.html
This commercial website describes a process for extracting products from broths with a high solid content, such as those found with fungal mycelia.
Vancomycin extraction
http://www.dynamicadsorbents.com/vancomycin.htm
This commercial website describes an alternative to standard ion exchange resins, using alumina in which the pore sizes can be adjusted to enhance recovery of products per unit material.
Supercritical fluids extraction in bioprocesses
http://www.jbiochemtech.com/index.php/jbt/article/viewFile/JBT215/51
This review article discusses the uses of supercritical carbon dioxide in product recovery for biotechnology.
Recovery of vanillin from fermentation media
http://blogs.rsc.org/gc/2011/08/01/sustainable-recovery-of-pure-natural-vanillin-from-fermentation-media-in-one-step/
This green chemistry blog briefly describes the use of a membrane evaporation system to quickly remove vanillin from fermenation broths without the use of solvents.