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. Author manuscript; available in PMC: 2015 Apr 16.
Published in final edited form as: Oncogene. 2013 Oct 28;33(42):4985–4996. doi: 10.1038/onc.2013.444

Figure 2. Expression of Aurora-A induces tamoxifen-resistance.

Figure 2

(A) Immunoblot analysis of MCF7 cells, which were stably transfected with HA-Aurora-A and pHM6 vector, with anti-HA and, -ERα and -actin antibodies. (B–D) Aurora-A- and pHM6 vector-transfected MCF7 cells were treated with and without tamoxifen for 72 hours and then were assayed for cell viability (B), apoptosis (C), and focus formation (D). Experiments were repeated three times, each experiment was triplicated. Error bars represent mean plus standard deviation. The asterisks denote significance (*P < 0.05 and ** P < 0.01).