Fig. 3.

Microdialysis measurements of extracellular levels of 5-HT (A) and its main metabolite 5-HIAA (B), and the absolute concentrations of both (C), in the MCx following fenfluramine administration in control and LPS pre-treated rats. Fenfluramine (10 mg/kg i.v.) was administered at t = 0 to animals that had received an i.p. injection of saline (solid line; n = 6) or LPS (0.5 mg/kg i.p.; broken line; n = 5) 6 h prior to t = 0. Data were calculated as a percentage of baseline (mean ± SEM values are shown).