Table 1. Resuming table of the criteria used for quantifying immunohistochemical staining and arbitrary score values assigned.

Biomarker expression
Intensity vs CtrII Step	Score Value assigned
− /± (same as the background or few higher than the background)	1
+ (higher than the background)	10
++ (much higher than the background)	20
Biomarker subcellular localization
% of positive cells	Score Value assigned
< or near 10%	5
>10% and <50%	10
>50%	20