Abstract
The pars triangular is a portion of Broca's area. The convolutions that form the inferior and caudal extent of the pars triangularis include the anterior horizontal and anterior ascending rami of the sylvian fissure, respectively. To learn if there are anatomic asymmetries of the pars triangularis, these convolutions were measured on volumetric magnetic resonance imaging scans of 11 patients who had undergone selective hemispheric anesthesia (Wada testing) to determine hemispheric speech and language lateralization. Of the 10 patients with language lateralized to the left hemisphere, 9 had a leftward asymmetry of the pars triangularis. The 1 patient with language lateralized to the right hemisphere had a significant rightward asymmetry of the pars triangularis. Our data suggest that asymmetries of the pars triangularis may be related to speech-language lateralization.
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- Adrianov O. S. Structural basis for functional interhemispheric brain asymmetry. Hum Physiol. 1979 May-Jun;5(3):359–363. [PubMed] [Google Scholar]
- Albanese E., Merlo A., Albanese A., Gomez E. Anterior speech region. Asymmetry and weight-surface correlation. Arch Neurol. 1989 Mar;46(3):307–310. doi: 10.1001/archneur.1989.00520390073019. [DOI] [PubMed] [Google Scholar]
- Binder J. R., Rao S. M., Hammeke T. A., Frost J. A., Bandettini P. A., Jesmanowicz A., Hyde J. S. Lateralized human brain language systems demonstrated by task subtraction functional magnetic resonance imaging. Arch Neurol. 1995 Jun;52(6):593–601. doi: 10.1001/archneur.1995.00540300067015. [DOI] [PubMed] [Google Scholar]
- Briggs G. G., Nebes R. D. Patterns of hand preference in a student population. Cortex. 1975 Sep;11(3):230–238. doi: 10.1016/s0010-9452(75)80005-0. [DOI] [PubMed] [Google Scholar]
- Chi J. G., Dooling E. C., Gilles F. H. Left-right asymmetries of the temporal speech areas of the human fetus. Arch Neurol. 1977 Jun;34(6):346–348. doi: 10.1001/archneur.1977.00500180040008. [DOI] [PubMed] [Google Scholar]
- Falzi G., Perrone P., Vignolo L. A. Right-left asymmetry in anterior speech region. Arch Neurol. 1982 Apr;39(4):239–240. doi: 10.1001/archneur.1982.00510160045009. [DOI] [PubMed] [Google Scholar]
- Foundas A. L., Leonard C. M., Gilmore R., Fennell E., Heilman K. M. Planum temporale asymmetry and language dominance. Neuropsychologia. 1994 Oct;32(10):1225–1231. doi: 10.1016/0028-3932(94)90104-x. [DOI] [PubMed] [Google Scholar]
- Foundas A. L., Leonard C. M., Heilman K. M. Morphologic cerebral asymmetries and handedness. The pars triangularis and planum temporale. Arch Neurol. 1995 May;52(5):501–508. doi: 10.1001/archneur.1995.00540290091023. [DOI] [PubMed] [Google Scholar]
- GOODGLASS H., QUADFASEL F. A. Language laterality in left-handed aphasics. Brain. 1954 Dec;77(4):521–548. doi: 10.1093/brain/77.4.521. [DOI] [PubMed] [Google Scholar]
- Galaburda A. M. La région de Broca: observations anatomiques faites un siècle après la mort de son découvreur. Rev Neurol (Paris) 1980;136(10):609–616. [PubMed] [Google Scholar]
- Geschwind N., Levitsky W. Human brain: left-right asymmetries in temporal speech region. Science. 1968 Jul 12;161(3837):186–187. doi: 10.1126/science.161.3837.186. [DOI] [PubMed] [Google Scholar]
- Gling I., Gloning K., Haub G., Quatember R. Comparison of verbal behavior in right-handed and non right-handed patients with anatomically verified lesion of one hemisphere. Cortex. 1969 Mar;5(1):43–52. doi: 10.1016/s0010-9452(69)80006-7. [DOI] [PubMed] [Google Scholar]
- Hardyck C., Petrinovich L. F. Left-handedness. Psychol Bull. 1977 May;84(3):385–404. [PubMed] [Google Scholar]
- Ingvar D. H. Serial aspects of language and speech related to prefrontal cortical activity. A selective review. Hum Neurobiol. 1983;2(3):177–189. [PubMed] [Google Scholar]
- Kulynych J. J., Vladar K., Jones D. W., Weinberger D. R. Three-dimensional surface rendering in MRI morphometry: a study of the planum temporale. J Comput Assist Tomogr. 1993 Jul-Aug;17(4):529–535. doi: 10.1097/00004728-199307000-00003. [DOI] [PubMed] [Google Scholar]
- Leonard C. M., Voeller K. K., Lombardino L. J., Morris M. K., Hynd G. W., Alexander A. W., Andersen H. G., Garofalakis M., Honeyman J. C., Mao J. Anomalous cerebral structure in dyslexia revealed with magnetic resonance imaging. Arch Neurol. 1993 May;50(5):461–469. doi: 10.1001/archneur.1993.00540050013008. [DOI] [PubMed] [Google Scholar]
- Mohr J. P., Pessin M. S., Finkelstein S., Funkenstein H. H., Duncan G. W., Davis K. R. Broca aphasia: pathologic and clinical. Neurology. 1978 Apr;28(4):311–324. doi: 10.1212/wnl.28.4.311. [DOI] [PubMed] [Google Scholar]
- Mugler J. P., 3rd, Brookeman J. R. Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magn Reson Med. 1990 Jul;15(1):152–157. doi: 10.1002/mrm.1910150117. [DOI] [PubMed] [Google Scholar]
- Nikkuni S., Yashima Y., Ishige K., Suzuki S., Ohno E., Kumashiro H., Kobayashi E., Awa H., Mihara T., Asakura T. [Left-right hemispheric asymmetry of cortical speech zones in Japanese brains (author's transl)]. No To Shinkei. 1981 Jan;33(1):77–84. [PubMed] [Google Scholar]
- Ojemann G. A. Individual variability in cortical localization of language. J Neurosurg. 1979 Feb;50(2):164–169. doi: 10.3171/jns.1979.50.2.0164. [DOI] [PubMed] [Google Scholar]
- SUBIRANA A. The prognosis in aphasia in relation to cerebral dominance and handedness. Brain. 1958 Sep;81(3):415–425. doi: 10.1093/brain/81.3.415. [DOI] [PubMed] [Google Scholar]
- Steinmetz H., Rademacher J., Huang Y. X., Hefter H., Zilles K., Thron A., Freund H. J. Cerebral asymmetry: MR planimetry of the human planum temporale. J Comput Assist Tomogr. 1989 Nov-Dec;13(6):996–1005. [PubMed] [Google Scholar]
- Steinmetz H., Volkmann J., Jäncke L., Freund H. J. Anatomical left-right asymmetry of language-related temporal cortex is different in left- and right-handers. Ann Neurol. 1991 Mar;29(3):315–319. doi: 10.1002/ana.410290314. [DOI] [PubMed] [Google Scholar]
- Teszner D., Tzavaras A., Gruner J., Hécaen H. L'asymétrie droite-gauche du planum temporale; á propos de l'étude anatomique de 100 cerveaux. Rev Neurol (Paris) 1972 Jun;126(6):444–449. [PubMed] [Google Scholar]
- Tonkonogy J., Goodglass H. Language function, foot of the third frontal gyrus, and rolandic operculum. Arch Neurol. 1981 Aug;38(8):486–490. doi: 10.1001/archneur.1981.00510080048005. [DOI] [PubMed] [Google Scholar]
- Wada J. A., Clarke R., Hamm A. Cerebral hemispheric asymmetry in humans. Cortical speech zones in 100 adults and 100 infant brains. Arch Neurol. 1975 Apr;32(4):239–246. doi: 10.1001/archneur.1975.00490460055007. [DOI] [PubMed] [Google Scholar]
- Willmore L. J., Wilder B. J., Mayersdorf A., Ramsay R. E., Sypert G. W. Identification of speech lateralization by intracarotid injection of methohexital. Ann Neurol. 1978 Jul;4(1):86–88. doi: 10.1002/ana.410040117. [DOI] [PubMed] [Google Scholar]
- Witelson S. F., Kigar D. L. Sylvian fissure morphology and asymmetry in men and women: bilateral differences in relation to handedness in men. J Comp Neurol. 1992 Sep 15;323(3):326–340. doi: 10.1002/cne.903230303. [DOI] [PubMed] [Google Scholar]
- Witelson S. F., Pallie W. Left hemisphere specialization for language in the newborn. Neuroanatomical evidence of asymmetry. Brain. 1973 Sep;96(3):641–646. doi: 10.1093/brain/96.3.641. [DOI] [PubMed] [Google Scholar]