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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1996 Jan 23;93(2):723–727. doi: 10.1073/pnas.93.2.723

Channel behavior in a gamma-aminobutyrate transporter.

J N Cammack 1, E A Schwartz 1
PMCID: PMC40121  PMID: 8570623

Abstract

Current produced by a gamma-aminobutyrate (GABA) transporter stably transfected into a mammalian cell line was observed in cell-attached and excised membrane patches. When GABA was absent, a fraction of the transporters produced cation-permeable channels. When GABA plus Na+ was on either side of the membrane, the majority of transporters produced a high-frequency current noise attributed to the movement of ions in an occluded pore.

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Selected References

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