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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: JAMA Ophthalmol. 2013 Nov;131(11):1412. doi: 10.1001/jamaophthalmol.2013.1902

Multiple pigmented basal cell carcinomas of the eyelids

Vivian Lee 1, Mark J Lucarelli 1, Nicholas A Ramey 1, Sherif S Khedr 1, Heather A Potter 1, Daniel M Albert 1
PMCID: PMC4017670  NIHMSID: NIHMS562444  PMID: 24232081

The content is available as a PDF (541.9 KB).

Figure 1.

Figure 1

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A 65-year-old man with a history of various facial skin cancers presents with multiple, bilateral, pigmented eyelid lesions, including an ulcerated lesion of the left lower eyelid with pigmentation at the margin of the lesion. Biopsies from the right medial canthus (bolded arrow), left upper and lower eyelids (arrows) were all diagnosed as pigmented nodular basal cell carcinomas.

Figure 2.

Figure 2

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A. Microscopic examination demonstrates a heavily pigmented nodular basal cell carcinoma from the right upper eyelid. B. Bleached sections reveal atypical basophilic tumor cells. C. Using a red reaction product to distinguish from inherent pigmentation in the lesion, tumor cells demonstrate positivity for S-100. (A. H&E × 200, B. Bleach × 200, C. ICH for S-100 (red) × 200).

Acknowledgments

Financial Support: None

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