Figure 5.

Cross-modal potentiation of TC-synapses is observed with deafening and is experience-dependent. (A) Regulation of TC-synapses in A1-L4. Top: Example traces of LEv-Sr²⁺-mEPSCs from NR, deaf (DF) and DE+DF (DD) group. A 5-ms duration LED light was delivered at the arrowhead to activate TC-synapses. Marks are the same as in Fig. 3. Bottom left: Average calculated LEv-Sr²⁺-mEPSC amplitude of TC-inputs (see Supplemental Experimental Procedures). Bottom right: Average raw LEv-Sr²⁺-mEPSC traces (without subtracting spontaneous events). (B) Cross-modal potentiation of TC-synapses in V1-L4 after deafening. Top: Example traces of LEv-Sr²⁺-mEPSCs. Marks are the same as in Fig. 3. Bottom left: Average calculated LEv-Sr²⁺-mEPSC amplitude of TC-inputs. *P < 0.008, t-test. Bottom right: Average raw LEv-Sr²⁺-mEPSC traces. See Table S3 for data.