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. Author manuscript; available in PMC: 2015 Mar 25.
Published in final edited form as: Circulation. 2014 Jan 7;129(12):1276–1285. doi: 10.1161/CIRCULATIONAHA.113.006611

Figure 2.

Figure 2

CaMKII-phosphorylation of RyR2 in CREM-mice increases prior to the onset of spontaneous AF. (A) Western blots showing age-dependent increase in levels of T287 auto-phosphorylation normalized to total CaMKII levels. (B) Western blots showing progressive increase in the level of S2814-phosphorylation normalized to total RyR2 levels. (C) Western blots showing the level of T17-phosphorylation normalized to total PLN levels. (D) Western blots showing the level of S2808-phosphorylation normalized to total RyR2 levels. Number in the bars indicated the number of animals studied *P<0.05, **P<0.01