Correction to Rapid Determination of Ionization Constants (pK_a) by UV Spectroscopy Using 96-Well Microtiter Plates

Four additional references have been added to the reference section, and the last column of Table 1 has been updated with the correct references.

Table 1. pK_a Values of Monoacidic, Monobasic, and Dibasic Compounds Determined by the 96-Well UV Spectrophotometric Method.

^aThe use of 2% v/v DMSO as cosolvent did not alter significantly the pK_a value of the test compounds. Working temperature = 30 °C. All pK_a were measured at constant ionic strength (I = 0.1 M) and concentration (C = 0.2 mM).

^bAnalytical wavelengths are determined at the maximum and minimum absorption values in the spectral difference plot.

^cExperiments were repeated at least three times.

^dStandard deviation.

^eExperimental pK_a values at 25 °C in water.

^■REFERENCES

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