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. Author manuscript; available in PMC: 2014 Jun 25.
Published in final edited form as: Biochemistry. 2013 Jun 14;52(25):4364–4372. doi: 10.1021/bi400342t

Figure 3. The effect of PARP inhibitor on NAD+ depletion.

Figure 3

BAEC were exposed to Deta/NO (500 µM) for 1 h prior to incubation without (black bars) and with menadione (20 µM, white bars) for an additional 4 h in the presence and absence of PARP-1 inhibitor, PJ-34 (10 µM). NAD+ levels were measured by HPLC and normalized to total protein. Values represent means ± SE; n = 3. * p < 0.05 compared to samples without Deta/NO, **p < 0.05 compared to samples without PJ-34.